Left Prefrontal Cortex Contributes to Motor Imagery: A Pilot Study

نویسندگان

  • Ina M. Tarkka
  • Dobrivoje S. Stokic
چکیده

Transcranial magnetic stimulat ion (TMS) over the motor cortex during motor imagery results in increased amplitudes of motor evoked potentials (MEPs) in muscles specific to the imagined movement. Functional MRI studies demonstrate that motor imagery involves a widespread neural network including prefrontal and parietal areas. The purpose of this pilot TMS study was to explore whether the left prefrontal cortex (PFC) is an active part of the motor imagery network. MEPs were recorded in 5 healthy subjects in t ibialis anterior (TA) muscles during the imagined right ankle dorsiflexion while the neural processes in the left PFC were disturbed by a single TMS pulse 300ms prior to the leg area stimulat ion with TMS. Motor imagery alone significantly increased MEP amplitudes in the target TA muscle compared to rest(440% on average, p=0.004). The left PFC stimulat ion prior to test stimulus significantly reduced the facilitat ion of MEPs during motor imagery (326%, p=0.031) butleft PFC stimulat ion had no effect when delivered during rest (103%). Th is suggests a functional link between the left PFC and sensorimotor cortex actively involved in motor imagery. Appropriately timed TMS over the left PCF most likely disturbed the kinesthetic working memory required for maintaining motor imagery.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Motor imagery in normal subjects and in asymmetrical Parkinson's disease: a PET study.

OBJECTIVE To investigate, using PET and H2(15)O, brain activation abnormalities of patients with PD during motor imagery. To determine whether motor imagery activation patterns depend on the hand used to complete the task. BACKGROUND Previous work in PD has shown that bradykinesia is associated with slowness of motor imagery. METHODS The PET study was performed in eight patients with PD wit...

متن کامل

Motor imagery during movement activates the brain more than movement alone after stroke: a pilot study.

OBJECTIVE To examine the neural correlates of motor imagery performed in conjunction with movement of the paretic arm after stroke. DESIGN Cross-sectional, cohort study. SUBJECTS Seven individuals in the chronic phase of stroke recovery (median (range): age: 58 years (37-73); time post-stroke: 9 months (4-42); upper extremity Fugl-Meyer motor score: 48 (36-64)). METHODS Participants activ...

متن کامل

Can ovariectomy and learning affect prefrontal cortex GABAAα1 receptor distribution in passive avoidance model in rats?

Introduction: The interaction between steroid hormones and neurotransmitters such as GABA has been proved. The regulation of muscimol binding to high-affinity GABAA receptors by estradiol and progesterone has been studied within distinct brain regions using in vitro quantitative autoradiography. There are few studies about the mechanism of the effect of steroid hormones on behaviors such as ...

متن کامل

تأثیر تحریک مکرر مغناطیسی فراقشری با فرکانس بالا در کاهش فعالیت سیستم فعال ساز رفتاری افراد سوء مصرف کننده مت آمفتامین

Objective: The present study was an attempt to examine the effect of repetitive Transcranial magnetic stimulation (rTMS) on the reduction of Behavioral Activation System's activity in right and left dorsolateral prefrontal cortex among methamphetamine abusers. Method: In the present study, single subject and multiple baseline research designs were used and repeated measurements observations wer...

متن کامل

The influence of individual motor imagery ability on cerebral recruitment during gait imagery.

Motor imagery (MI) is often used in combination with neuroimaging techniques to study the cognitive control of gait. However, imagery ability (IA) varies widely across individuals, potentially influencing the pattern of cerebral recruitment during MI. The aim of the current study was to investigate this effect of IA on the neural correlates of gait control using functional magnetic resonance im...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013